Necessity of the Outside Filter in Preparation for an Infuser Pump Using Glass Ampoules

概要

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For preparation using an infuser pump, the use of a filter is recommended on package inserts. However, there are no concrete data on the necessity of the outside filters. Therefore, we compared the number of particles in the preparation fluid in the infuser pump with and without using a filter. Particles with a diameter of 1.3-100 μm were counted using a light blockage particle counter KL-04 (Rion K.K., Tokyo, Japan). Without using a filter, the mean numbers of particles with diameters of 1.3-5, 5-10, and > 10 μm were 187.4 ± 76.6, 6 ± 3.3, and 1 ± 1, respectively. Using a filter, the mean numbers of particles with diameters of 1.3-5, 5-10, and > 10 μm were 12.4 ± 4.2, 1.2 ± 0.8, and 0.2 ± 0.4, showing decreases in each particle size range including significant decreases in particles with diameters of 1.3-5 and 5-10 μm. The preparation using the outside filter was necessary for removing contaminating particles.
日本医療薬学会の論文