多量の浸出液を伴うがん性悪臭に対してダラシンパテが有用であった一例と軟膏基剤の吸水性の評価
スポンサーリンク
概要
- 論文の詳細を見る
Cancerous malodor remarkably decreases the quality of life of patients. However, in the absence of a standard topical therapy for it, we have to use a hospital preparation.We report the case of a patient with extensive malodorous malignant effusion who was successfully treated with clindamycin-pate. The patient was a 49-year-old man who had malignant melanoma. The melanoma had spread to the intracranial region and left axillary and para-aortic lymph nodes. The metastatic lesion in the left axillary lymph node released a strong odor. Cadexomer-iodine ointment was first used for treatment of the lesion but was ineffective against the effluvium so we changed it to clindamycin-pate.In a survey of hospital staff, 87.5% stated that the foul smell had disappeared after treating the patient with clindamycin-pate. Clindamycin-pate has been seen to exhibit significant antimicrobial activity against gram-positive and anaerobic bacteria and this is probably the reason for its effectiveness against the foul smell. It also absorbed a considerable amount of the effusion, eliminating the need to use carboxymethylcellulose sodium salt (CMC-Na). Therefore, clindamycin-pate is considered to be an effective adjuvant therapy for controlling malodorous effusion in cancer patients. Furthermore, in a comparison of hydrophilia with various external preparations, clindamycin-pate was found to have remarkable moisture absorption capability, providing further evidence of its usefulness in the control of effusions.
- 日本医療薬学会の論文
日本医療薬学会 | 論文
- O17-003 視覚障害者に対する手技指導の標準化を目的とした視覚障害擬似体験インスリン注射院内実習(一般演題 口頭発表,糖尿病/後発医薬品,医療薬学の創る未来 科学と臨床の融合)
- 20H-16 Basal-Bolus療法におけるインスリンデテミルの有効性(使用状況調査・意識調査,来るべき時代への道を拓く)
- 30-P2-43 2種類のインスリン試薬を用いた化学発光酵素免疫測定法によってFactitious hypoglicemiaを証明しえた一例(副作用・有害事象,社会の期待に応える医療薬学を)
- 28-04-20 ペン型インスリン注射器の精度に及ぼす注入時抵抗とカートリッジ内気泡の影響
- P-610 ファブリー病に対する「ファブラザイム^[○!R]」投与時の「過敏反応発現時の対処方法」の一部改変により副作用防止に至った1症例(8.有害事象・副作用(基礎と臨床)1,医療薬学の未来へ翔(はばた)く-薬剤師の薬剤業務・教育・研究への能動的関わり-)