妊婦における高血圧治療薬の産婦人科医と内科医の使用実態調査‐カルシウム拮抗薬を中心として‐:-カルシウム拮抗薬を中心として-
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Pregnancy is a contraindication for oral calcium blockers in Japan.However,based on the existence of a guideline for the treatment of hypertension and a previous survey,it seems that oral calcium blockers are in fact used for the management of hypertension in pregnant women.With this in mind,we conducted a questionnaire survey on experience of using calcium blockers for the management of hypertension in pregnancy and attitudes towards this.We sent the questionnaire to 291 hospitals and 300 departments of internal medicine in hospitals with obstetrics and gynecology facilities,and received the responses by mail.We received 116 responses from the hospitals and 52 from the obstetrics and gynecology facilities,115 and 50 of which were analyzable,respectively.Although 75% of the hospitals had unified policies for medication in this respect,policies varied among hospitals,and between obstetricians and internists.Approximately half of the respondents were using calcium blockers,with most of them selecting sustained release formulations of nifedipine or nicardipine and only small number of them using long-acting calcium blockers.While many respondents (67%) were considering using calcium blockers for the management of the hypertension in pregnancy,it appeared that other doctors felt that their use should be limited because it was unclear whether they were safe in pregnancy or not,or due to the contraindication in Japan.Further studies are therefore required to clarify the safety of calcium blockers for pregnant women and fetuses.
- 日本医療薬学会の論文
日本医療薬学会 | 論文
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