特定抗菌薬使用届出制導入による抗菌薬の使用量と抗菌力の推移

概要

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It is important that anti-microbial drugs are used properly to prevent increases in resistant bacteria.The Infection Control Team (ICT) of Nagara Medical Center introduced a reporting system in which the use of specific anti-microbial drugs,such as fourth generation cephalosporins,carbapenems,new quinolones,and anti-MRSA drugs,was restricted.As a result,there was an increase in prescriptions for penicillin and third generation cephalosporins and a decrease in prescriptions for the restricted drugs.We consider that our reporting system made doctors think more carefully about selecting anti-microbial drugs,resulting in the change in usage pattern.With this change in the use of anti-microbial drugs,the number of bacteria detected decreased and there was also a decrease in the minimum inhibitory concentration (MIC) for MRSA and Pseudomonas aeruginosa.In conclusion,our restrictions on specific anti-microbial drugs decreased their usage and there was also a decrease in the number of bacteria detected.
日本医療薬学会の論文