抗がん剤用安全取扱器具　ＰｈａＳｅａｌ　ｓｙｓｔｅｍの操作性の評価

概要

論文の詳細を見る
Most antineoplastic agents used in chemotherapy are cytotoxic and could damage the health of medical staff when they are exposed to them. To counter this risk, a safety cabinet is commonly used. Since such cabinets have been reported to be lacking, the PhaSeal® system (PS-s, a sealed-type safety device) was developed for use with the safety cabinet, and has been reported to be effective in studies done in Europe and the US. We tested the PS-s at a medical institution in Japan with regard to suitability and easy of operation. In the testing, the PS-s was compared with the conventional system (C-s) as regards preparation time using ten pharmacists and ten nurses as subjects. Afterwards, a questionnaire survey on the test results was conducted.The total preparation time required for C-s was 42.6±11.15 seconds and that for PS-s was significantly longer at 63.3±14.99 seconds (p<0.01). The time required for aspiration of drug from the vial was 27.2±9.08 seconds for C-s and 17.7±5.53 seconds for PS-s, which was significantly shorter (p<0.01). The questionnaire survey results indicated that PS-s was much safer to use for medical professionals but their opinions were divided as to whether it was easier to operate or not. We concluded that PS-s would be useful in the preparation of cytotoxic anticancer agents if medical staff could become more familiar with its operating procedure.
日本医療薬学会の論文