Midline Malignant Reticulosisの1剖検例
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概要
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A 67-year-woman of midline malignant reticulosis was reported. She complained of nasal obstruction and fever, and it was found that her nasal cavity was covered by granulation tissue and crustae. Biopsies obtained from her nasal granulation tissue showed atypical reticulum cell proliferations with inflammatory cell infiltration and necrosis. Finally, she died of dissemination of atypical and pleomorphic reticulum cells mainly in the spleen, liver and visceral lymph nodes. An infiltrative and pleomorphic character of atypical reticulum cells with inflammatory cells was compatible with midline malignant reticulosis. Disappearance of her nasal changes by VEMP therapy was noted.
- 一般社団法人 日本血液学会の論文
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