多発性骨髄腫におけるVinca Alkaloidの試用経験

概要

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There are many reports that Vinca alkaloid therapy is effective for leukemia in children, malignant lymphoma, etc. We applied this therapy to seven courses in six patients of multiple myeloma in which therapies with such agents as cyclophosphamide, steroid hormones, etc. had been ineffective. Of these seven courses, the therapy proved to be effective in three couses, but in the remaining four, inffective. In all courses, reduction of the peripheral leukocyte was observed as a side effect. Although this therapy may not be adopted as the first choice for multiple myeloma, it is considered as an alternative when other therapeutic regimens have been inffective.
一般社団法人日本血液学会の論文