強皮症における体表面弾性特性の非接触的計測
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概要
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We have developed a system for measuring the viscoelastic property of the skin that involves no direct contact with the body surface. By applying the air pressure, the quantitative value of elastic modulus was calculated based on Boussinesq equation with the displacement of the body surface which was non-contact measured using laser displacement meter. This system needs about 3s measuring time and the accuracy of the elastic modulus was within 10% error range. In this study, the elastic moduli of the extensor and flexor forearm surface were measured for the determination of standard range of these regions so as to compare these with that of systemic sclerosis. As the results, no significant difference was recognized in the laterality of the forearm and the difference between extensor and flexor position. On the other hand, the normal forearm elastic modulus measured in the male showed the tendency that was larger than that of female, and the elastic modulus showed decrease with age in both of male and female. To applying this system to measure the forearm of systemic sclerosis patients, loading air pressure was changed to higher level in compare with normal subjects. Obtained elastic modulus was compared with modified Rodnan total skin thickness score (m-Rodnan TSS) that was used regularly clinically. In the higher m-Rodnan TSS in the systemic sclerosis patients, the elastic modulus was also higher than that of normal subjects. These results suggested that the clinical efficacy of diagnosis will increase by adding the quantitative numerical value obtained by this method to four stages of indexes of skin score. This system is clinically useful to quantitatively evaluate the body surface as the elastic modulus, because of the non-invasive and non-contact measurement in addition to satisfactory operability of the system.
- 一般社団法人 日本生体医工学会の論文
一般社団法人 日本生体医工学会 | 論文
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