人工透析液製造工程での微生物制御におけるヒノキチオール利用の可能性

概要

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An effective microbial contamination control is certainly requested for the high quality sanitary condition of hemodailysate preparation. To gratify this request, several disinfectants and the other bactericidal processes are employed to make clean condition for the inner tubes or some water reservoir of hemodialysate preparing instrument. Particularly, the hot water disinfection is widely employed many hospitals and hemodialysis therapy section because this procedure do not uses any drugs or chemical substances. Whereas hot water disinfection killed most of bacteria in hemodialysate preparation instrument, it was also confirmed that the bacteria was recovered immediately after heat treatment. From these backgrounds, the authors attempted to keep clean condition after hot water disinfection treatment using Hinokitiol which has been known as an essence of the forest bath. This paper demonstrated that the antibacterial activity of Hinokitiol against clinically isolated bacteria and its heat stability. These findings indicated that Hinokitiol could employ for useful supplement of hot water disinfection and we also propose a newly hot water disinfection system using Hinokitiol treatment.
一般社団法人日本生体医工学会の論文