Biomonitoring of Oxidative DNA Damage in Traffic Policemen Exposed to Urban Air Pollution
スポンサーリンク
概要
- 論文の詳細を見る
The urinary excretion of 8-hydroxy-2'-deoxyguanosine (8-OHdG) has been used as a biomarker of oxidative DNA damage in both the clinical and occupational setting. The urinary 8-OHdG in traffic policemen posted at busy traffic junctions were estimated along with the control population away from the busy traffic junctions those doing administrative job. A total of 105 urinary samples (60 samples of traffic policemen and 45 samples of control population) were collected for estimation of 8-OHdG and analyzed using enzyme linked immunosorbent assay (ELISA). The mean 8-OHdG was significantly higher (13.42±1.61) μg/g creatinine) than those of control group (9.34±1.36 μg/g creatinine) (p<0.05). The study showed that urinary 8-OHdG is associated with occupational exposure and other lifestyle factors.
- 日本環境変異原学会の論文
日本環境変異原学会 | 論文
- P-145 化学物質の変異原性に関するEU分類とドイツMAK分類の比較(ポスターセッション)
- P144 生殖細胞変異原のGHS分類基準適用における問題点
- P-98 GHSにおける生殖細胞変異原性物質の分類(ポスター(2))
- リスクアセスメントにおける遺伝毒性 : 海外の動向と視点(第33回大会シンポジウム1「発がん性と遺伝毒性の閾値 : リスクアセスメントにおける問題点」)
- S2-4 環境汚染物質による野生生物のリスクを評価するための科学的方法(シンポジウム2:「環境と食の安全性にサイエンスが果たす役割」)