Patterning of Molar Tooth Roots in Mammals
スポンサーリンク
概要
- 論文の詳細を見る
Tooth morphogenesis is regulated by reciprocal interactions between the dental epithelium and odontogenic mesenchyme. As tooth roots are fundamental structures of the tooth support system, the morphology and functions of the roots are very important. However, basic information on the morphology of tooth root patterning and the molecular mechanism of root morphogenesis is largely unavailable. Following tooth crown formation, the dental epithelium forms a double-layered Hertwig's epithelial root sheath (HERS) derived from inner and outer enamel epithelium. Previous studies have reported that HERS plays an important role in tooth root development. Here, we report the correlation between the number of major cusps of the tooth crown and number of tooth roots of first molar and last premolar teeth in several extant mammals. We also discuss the molecular mechanism of tooth root patterning by introducing studies of mouse mutants and human syndromes associated with an abnormal molar morphology.
- 歯科基礎医学会の論文
歯科基礎医学会 | 論文
- 口腔レンサ球菌のベータディフェンシン感受性の多様性とその機構の解析
- ココアによる歯周病関連菌に対する抗菌効果
- Candida albicansに対するDefensinの抗菌活性の検討
- 唾液腺腺様嚢胞癌の偽嚢胞腔内の免疫グロブリン
- 破骨細胞が産生するcathepsin KとMMP-9の局在について : 肺癌骨転移モデルを用いた検討