Tubulointerstitial Nephritis and Uveitis Syndrome in Two Siblings.
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概要
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Two Japanese sisters with persistent uveitis showed significant increased levels of urinary β-2 microglobulin. A percutaneous renal biopsy performed in the younger sister revealed tubulointerstitial nephritis (TIN) with helper/inducer T cell infiltrates. Also, abnormal 67-gallium accumulation in the kidneys, suggesting TIN, was observed in the other one at the same time. Although patients with the syndrome of tubulointerstitial nephritis and uveitis (TINU) have been reported to date, its occurrence in siblings has rarely been seen. Both of them shared same human leukocyte antigen (HLA) DR6, suggesting the potential association between HLA-DR6 and TINU.
- 東北ジャーナル刊行会の論文
東北ジャーナル刊行会 | 論文
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