Strong Immunoreactivity of Platelet-Derived Growth Factor and Its Receptor at Human and Mouse Neuromuscular Junctions.
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概要
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Platelet-derived growth factor (PDGF) and its α-receptor were localized at human and mouse neuromuscular junctions (NMJs) using specific polyclonal antibodies against each, anti-PDGF-A and anti-PDGF α-receptor, respectively. By applying double fluorescence labeling, immunoreactivity for PDGF and its receptor was closely co-localized with acetylcholine receptors, which were identified with α-bungarotoxin. PDGF might be involved in the interaction between the presynaptic and postsynaptic components. This is the first demonstration of PDGF and its receptor concentrated at human and mouse NMJs.
- 東北ジャーナル刊行会の論文
東北ジャーナル刊行会 | 論文
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