Behavioral Resistance of Caenorhabditis elegans Against High-LET Radiation Exposure
スポンサーリンク
概要
- 論文の詳細を見る
Effects of high linear energy transfer (LET) radiation on the functions of the nervous system is a potential risk in interplanetary manned space missions. However, little is known about how the nervous system is protected against high-LET radiation exposure. The analysis of high-LET radiation resistant animals would be therefore important for space missions. Here, we investigated the resistance to high-LET radiation exposure for two behaviors of the nematode, Caenorhabditis elegans, which is known as a model organism for the nervous system. Tested behaviors were locomotion and chemotaxis to NaCl. In addition, egg hatchability was examined as an indicator of high-LET radiation sensitivity. Relative biological effectiveness (RBE) of high-LET radiation (12C, 18.3 MeV/u, LET = 113 keV/μm) relative to low-LET radiation for hatchability was 4.5, whereas RBEs for locomotion and chemotaxis were 1.4 and 1.1, respectively. This study shows that the behavioral system for locomotion and chemotaxis of C. elegans is highly resistant to high-LET radiation exposure.
- 日本宇宙生物科学会の論文
日本宇宙生物科学会 | 論文
- 須田立雄先生「ビタミンDと骨に関する研究」2001年度日本学士院章を受賞
- 放射線による突然変異と発癌の原因となる長寿命ラジカル
- TANPOPO : 有機物と微生物の宇宙空間曝露と微隕石及び微生物の捕集実験
- Radiation Doses for Human Exposed to Galactic Cosmic Rays and Their Secondary Products on the Lunar Surface
- 各種の筋活動抑制に対するラット足関節底屈筋の反応