ループ利尿剤と耳鳴
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概要
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After loop diuretic administration, transient hearing loss or tinnitus aurium occurs in some cases, but the clinical features of tinnitus aurium are largely unknown. The audiogram of patients given loop diuretics is usually of the flat type and its grade is middle. In this respect, deafness due to loop diuretics is similar to aspirin induced deafness. The morphological, biochemical and electrophysiological changes caused by both drugs are compared and differences are seen in their pathology. Thus, the genesis of tinnitus aurium remains obscure. Loop diuretics act upon stria vascularis. Its characteristics is useful in the investigation of inner ear deafness or tinnitus.
- 耳鼻と臨床会の論文