上顎癌116症例の遠隔成績:特に5FU単独及びBUdR・5FU混合動注三者併用療法の比較検討

概要

論文の詳細を見る
One hundred and sixteen cases of the maxillary carcinoma have been treated in Tohoku Univer-sity Hospital from 1972 to 1978. There were 83 males and 33 females (5 to 2 ratio) patients. The majority of our patients, 75.9%, were in the sixth, seventh and eighth decades of life. The following multiple approaches were used in an effort to evaluate the best method of treatment. Group A... I-A infusion chemotherapy (5FU) irradiation necrotomy +maxillectomy...37cases Group B...I-A infusion chemotherapy (BUaR+5FU) irradiation necrotomy +maxillectomy...39cases Group C...maxillectomy+post-op irradiation with or without chemotherapy...21cases Group D... miscellaneous...19cases The five years relative survival rates and two years local control rates of each group are shown in the following table, and no significant difference was found among them. On the other hand, the obvious difference of the relative survival rates was found in the two groups which were classified by the Shimozato's criteria. The 33 cases of Type I & II group revealed 26.0 & plusmn;15.6% relative survival rate, whereas 37 cases of Type III & IV group showed 80.3 & plusmn;15.2%. This results seem to indicate that the best treatment for maxillary carcinoma is to obtain complete degenerations of the cancer cells by the end of the primary combined therapy, prior to maxillectomy.
耳鼻と臨床会の論文