第79回日本耳鼻咽喉科学会総会シンポジウムIII 反覆性耳下腺腫脹:臨床像と病因についての検討
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概要
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In 79 cases with recurrent parotid swelling, the most frequent were recurrent parotitis in childhood and Sjögren syndrome. Recurrent parotid swelling was seen in about 1/2 of cases of Sjögren syndrome.<BR>Recurrent parotid swelling in Sjögren syndrome was assumed to be due to secondary to ascending bacterial infection superimposed on autoimmune change of the salivary glands. It is sometimes difficult to differentiate Sjögren syndrome in its early stage from non-specific recurrent parotitis.<BR>However in Sjögren syndrome pathological changes occur in all the salivary glands including minor salivary glands and sialography shows either punctate dilatation of the peripheral duct or diffuse minute leakage shadow of the contrast media from the ductal system both in bilateral parotid and also in submandibular glands. This is seen before sialometry reveals definite reduction of salivary secretion.<BR>To evaluate influence of mumps and other virus infection on onset and on acute exacerbation of recurrent parotitis in childhood, virological study of complement fixation test, hemagglutine inhibition test and neutralization test was performed.<BR>Onset of this disorder was not associated with mumps.<BR>But various virus infection was manifested on acute exacerbation.<BR>This was assumed to cause ascending bacterial infection by lowering systemic resistance.<BR>Serum IgA, IgG, IgM and salivary IgA were measured by immunodiffusion method which did not reveal lowering of these immunogloblin level in subjects with recurrent parotitis in childhood.
- 耳鼻と臨床会の論文