両側上顎癌の3症例
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概要
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During the period from 1960 to 1971 three cases of carcinoma of the bilateral maxillary sinuses were treated at our clinic.<BR>Case 1. A forty-three-year-old female suffered from carcinoma of the bilateral maxillary sinuses with an interval of seven years. The first carcinoma was developed on the right side and treated with partial maxillectomy successfully. The second malignancy on the left side was treated also successfully with a combined therapy which consisted of radiation, chemotherapy and necrotomy followed by partial maxillectomy. Histological examinations revealed squamous cell carcinoma on the both sides.<BR>Case 2. A fifty-two-year-old female suffered from cancer of the right maxillary sinus in 1958 and received total maxillectomy at another university hospital. No information of histological findings was available. After the interval of twelve years she developed carcinoma of the left maxillary sinus in 1970. The second neoplasm was treated with a combined therapy followed by total maxillectomy. Histological examination revealed squamous cell carcinoma. She died of pulmonary disease fourteen months after the surgery.<BR>Case 3. A forty-seven-year-old male developed carcinoma of the bilateral maxillary sinuses with an interval of about three months. No direct continuity between the two malignancies was found clinically. A combined therapy followed by surgery was given on each side. Histological examinations revealed squomous cell carcinoma bilaterally.<BR>On the basis of careful analysis of the history, clinical findings and histological evidences, we concluded that in the first two cases each carcinoma was developed independently hence primary multiple malignant neoplasms. It was not able to determine whether the bilateral malignancies were independent each other or not in the third case.
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