慢性副鼻腔炎に対するリゾチームの検討:上顎洞粘膜の病理組織学的検査成績

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The authors applied "Lisozym"( a sort of Mucopolysaccharase generally existing in living bodies) to 35 patients suffering from chronic sinusitis, and examined its effects pathohistologically. 90 mg of this drug a day was administered internally, from immediately after the operation of one side till the next operation of the other side (7-23 days). About the obtained 70 mucosas, the efficiency of the drug was estimated by means of the extend of oedema, dilatation of capillary vessels, cell infiltration, exforation of epitheliums or by means of the condition of cilia.<BR>The efficiency rate was 54.2% and no after-effect was observed. And the efficiency was higher in the patients below twenty years, and became remarkable after 2 weeks administration of it.<BR>" Lisozym" is supposed to be efficient in little children to whom operation is difficult to be applied, and is recommended to be tried for 3 weeks at least.
耳鼻と臨床会の論文