Adsorption of 99mTc Labeled HMDP and MDP on Hydroxyapatite.
スポンサーリンク
概要
- 論文の詳細を見る
<I>The in vitro adsorption on hydroxyapatite (HAP) of</I> <SUP>99m</SUP>Tc-<I>hydroxymethylene diphosphonate</I> (<SUP>99m</SUP>Tc-<I>HMDP) and</I> <SUP>99m</SUP>Tc-<I>methylene diphosphonate</I> (<SUP>99m</SUP>Tc-<I>MDP), which are used as bone imaging agents, was studied. The adsorption of both diphosphonates was carried out in the concentration of 1.2×10</I><SUP>-5</SUP> <I>and</I> <SUP>4.7×10</SUP><SUP>-5</SUP> <I>mol/dm</I><SUP>3</SUP>. <I>Radioactivities of the filtrate and precipitate taken from the adsorptive solution were measured, and the filtrate was analyzed with radio-thinlayer chromatography. The</I> <SUP>99m</SUP>Tc <I>compounds forming polymers, as previously reported, were remained partially on the precipitate paper at the initial stage of adsorption. The amount of</I> <SUP>99m</SUP>Tc-<I>HMDP and MDP adsorbed for 1 h was 84% and 77%, respectively, the former adsorbed on HAP to a greater degree than did the latter. The compounds adsorbed on HAP are in a state of adsorption equilibrium with those in the solutions even after adsorbing for 3 h, and seem to be stable</I>.
- 社団法人 日本アイソトープ協会の論文
社団法人 日本アイソトープ協会 | 論文
- Distortion of Pulse Height Spectra Due to Absorbers in the Measurement of Low-energy .BETA.-rays with a Silicon Detector.
- タイトル無し
- Estimation of Angular Distributions of the Low-Energy .BETA.-Ray Emission from a Sealed Source.
- Comparison of SPECT images with four kinds of 99nTc collimators.
- Cross Talks on to 201Tl- and 123I-Photopeak Windows with Simultaneous Administration of Them, Using of a Gamma Camera.