Effect of Chitosan and Alginate on the Biokinetics of Radiostrontium in Rats.
スポンサーリンク
概要
- 論文の詳細を見る
<I>Chitosan derived from chitin which is a cellulose-like biopolymer distributed widely in nature, especially in shellfish, insects, fungi and yeast, is known to be one of the natural chelating agents. The purpose of the present study is to investigate whether chitosan can be applied to the animal and human body in order to reduce the bioavailability of radiostrontium in foods</I>.<BR><I>Chitosan solution was orally given and immediately after then</I> <SUP>85</SUP>SrCl<SUB>2</SUB> <I>was administered to rats using a stomach tube. The whole-body retention of</I> <SUP>85</SUP>Sr <I>determined by in vivo counting was lower than that of control rats which were not given chitosan. The activity ratio in urine and f eces f or chitosan-treated rats was higher than control rats</I>.<BR><I>Ten percent of alginate food was given to rats during 10 days and</I> <SUP>85</SUP>Sr <I>was administered orally. The whole-body retention of</I> <SUP>85</SUP>Sr <I>alginatetreated rats was decreased sharply compared with control rats</I>.<BR><I>These results suggested that chitosan and alginate can be used as a drug to reduce bioavailability from gastrointestine of ingested radio strontium</I>.
- 社団法人 日本アイソトープ協会の論文
社団法人 日本アイソトープ協会 | 論文
- Distortion of Pulse Height Spectra Due to Absorbers in the Measurement of Low-energy .BETA.-rays with a Silicon Detector.
- タイトル無し
- Estimation of Angular Distributions of the Low-Energy .BETA.-Ray Emission from a Sealed Source.
- Comparison of SPECT images with four kinds of 99nTc collimators.
- Cross Talks on to 201Tl- and 123I-Photopeak Windows with Simultaneous Administration of Them, Using of a Gamma Camera.