Evaluation of additional absorbed radiation dose from radioactive impurities in radiopharmaceuticals.
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概要
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<I>The additional absorbed radiation doses to total body from radioactive impurities in radiopharmaceuticals were estimated for a total of 10 samples</I> (<I>i.e., </I> <SUP>99m</SUP>Tc <I>generator eluates, </I> <SUP>99m</SUP>Tc <I>solutions, </I> <SUP>67</SUP>Ga, <SUP>81m</SUP>Kr <I>generator eluates, </I><SUP>111</SUP>In, <SUP>123</SUP>I, <SUP>201</SUP>Tl, <SUP>75</SUP>Se, <SUP>197</SUP>Hg, <SUP>198</SUP>Au) <I>selected from commonly used radiopharmaceuticals. The radioactive impurities in radiopharmaceuticals used in this estimation were previoulsy identified. The radiation doses were calculated according to the MIRD procedures, assuming each radionuclide to be uniformly distributed throughout the body. In the case of the cyclotron-produced radioisotopes and</I> <SUP>198</SUP>Au, <I>the additional total body absorbed doses from impurities were found to be rather high: 280% for</I> <SUP>123</SUP>I, <I>55% for</I> <SUP>81m</SUP>Kr, <I>5% for</I> <SUP>198</SUP>Au, <I>4% for</I> <SUP>111</SUP>In <I>and 2% for</I> <SUP>201</SUP>Tl. <I>The absorbed doses due to impurities in the other radioisotopes were less than 1%.</I>
- 社団法人 日本アイソトープ協会の論文
社団法人 日本アイソトープ協会 | 論文
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