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<I>In order to know the potential merits of</I> <SUP>99<I>m</I></SUP>Tc-<I>pyrophosphate</I> (<SUP>99<I>m</I></SUP>Tc-<I>PYP) skeltal imaging, a comparative study was carried out by administering to the rabbit</I> <SUP>85</SUP>Sr-<I>chloride</I> (<SUP>85</SUP>Sr), <I>classical bone-seeking agent, and</I> <SUP>99<I>m</I></SUP>Tc-<I>PYP simultaneously. Radioisotopic distribution was investigated as regards their deposition in the pelvic bones, and sharpness of the skeletal scintigrams, too.</I><BR><I>Both agents were remarkably afnitive to the skeletal system and there were remarkably differences in their temporal deposition pattern. Marked deposition was observed of either agent in the metaphyses. With</I> <SUP>99<I>m</I></SUP>Tc-<I>PYP, the vertebral and costal systems were delineated symmetrically and each vertebral body was distinctly depicted as such</I> <SUP>99<I>m</I></SUP>Tc-<I>PYP many possess the following merits over</I> <SUP>85</SUP>Sr; (1) <I>owing to its physical properties, sullieiently large radioactivity of</I> <SUP>99<I>m</I></SUP>Tc-<I>can be administered; (2) body burden of radiation absorption is reduced; (3) skeletal scintigrams of high quality are obtainable in ashort period of time.</I>
- 社団法人 日本アイソトープ協会の論文
社団法人 日本アイソトープ協会 | 論文
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