A Comparative Study, by Objective Quantization Using Microdensitometry, between Cardiac Pool Images Obtained Using Red Blood Cells Labeled <I>in vivo</I> with <SUP>99m</SUP>Tc and Using <SUP>99m</SUP>Tc-human Serum Albumin
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<I>A detailed comparison was performed subjectively and objectively between the quality of cardiac pool images obtained using red blood cells lebeled in vivo with</I> <SUP>99<I>m</I></SUP>Tc <I>and</I> <SUP>99<I>m</I></SUP>Tc-<I>human serum albumin. Both methods gave cardiac pool images of high quality. In order to compare the images between both methods, the microdensitometry was performed in both images of the same patients along the line drawn through the center of the left ventricular image and the septal image. Measuring the highest density of left ventricle as C<SUB>L</SUB> and that of septum as C<SUB>s</SUB>, the index I (I<SUB>I</SUB>) was obtained as (C<SUB>L</SUB>-C<SUB>s</SUB>) and the index II (I<SUB>I</SUB>) was calculated as (C<SUB>L</SUB>-C<SUB>s</SUB>) / (C<SUB>L</SUB> +C<SUB>s</SUB>) . The objective comparison was performed by these indices. The method using red blood cells labeled in vivo with </I><SUP>99<I>m</I></SUP>Tc <I>resulted in subjectively superior images and a higher left ventricle-to-septum density ratio in cases of control groups, myocardial infarction and aortic valvular disease. But in cases of mitral valvular disease and arrhythmia the in vivo method resulted in inferior or almost equal to the method obtained using</I> <SUP>99<I>m</I></SUP>Tc-<I>HSA. The quantitative indices used in this study can be thought to represent the contrast between the left ventricular image and the septal image. A better contrast may be obtained in a better image and may contribute more to the clinical diagnosis. From the point of clinical contribution, both agents are suitable for radionuclide imaging of the cardiac chambers. And the adequate combination of both method may be useful for clinical diagnosis.</I>
- 社団法人 日本アイソトープ協会の論文
社団法人 日本アイソトープ協会 | 論文
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