Reevaluation of 131I-Thyroid Uptake Rate in Euthyroid and Various Thyroid Disorders

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We reported on the 131I-thyroid uptake rate in various thyroid disorders more than ten years ago, but method and instrument of thyroid uptake was greatly improved ever since. This report is the results of 131I thyroid uptake rate in 400 cases of euthyroid and 300 cases of hyperthyroid, 20 cases of hypothyroid, 230 cases of non toxic diffuse goiter, 140 cases of non toxic nodular goiter, 30 cases of malignant goiter, 20 cases of subacute thyroiditis and 50 cases of chronic thyroiditis. In 400 cases of euthyroid and 300 cases of hyperthyroid, no significant differences of 131I thyroid uptake rate was seen depending on the sex, age and season of the subjects. Lower 24 hour uptake than 3 or s hour uptake was seen in 7.3% of euthyroid cases, 30.0% of hyperthyroid cases, 7.9% of cases of non toxic diffuse goiter and 5.5% of cases of non toxic nodular goiter. When 20% was used as the upper limit of normal for 3 hr uptake value, the diagnostic error was 2.8%. When 35 or 40% and 45% were used as the upper limits for s and 24 hr uptake respectively, the respective diagnostic errors were 1.8 and 2.4%. In 150 cases of hyperthyroidism successfully treated with 131I, 131I thyroid uptake after treatment was 1.4-70. 9 (average 29.2%) and 39% and 15.3% of the cases showed 131I thyroid uptake rate higher than 40% or lower than 10% respectively.
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