A CASE OF CHINESE RESTAUTRANT SYNDROME WITH MULTIPLE FOOD ALLERGY
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概要
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We reported a case of an asthmatic boy with chinese restaurant syndrome. The symptoms induced by oral challenge of monosodium glutamate were urticaria and asthmatic attack (wheezing and cough) and they appeared within 15min. He was sensitive to many allergens such as, hen's egg, cow's milk, soy bean, some kinds of fish, some kinds of fruits and house dust mite. Skin examination and histaminereleasing test by monosodium glutamate were performed and the results were negative. Serum gastrin concentration significantly elevated after oral challenge of monosodium glutamate. These results suggest that non-allergic mechanism, suchas gastrin mediated histamine release, may be involved in the development of these symptoms.
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