THE OBSTETRICAL FACTORS AT BIRTH AND THE CORD SERUM IgE LEVELS

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We studied the relationship between the cord serum IgE levels and the obstetrical factors at birth.The maternal peripheral serum IgE levels at delivery were measured by radio immuno sorbent test (RIST) and the cord serum IgE levels by full automation enzyme immuno assay system, IMx.1. The mean levels of maternal and the cord serum IgE were 142.3±320.8IU/ml (n=226) and 0.476±0.9IU/ml (n=242) respectively.2. A significant correlation (r=0.996, n=80) was observed between the levels of arterial and venous cord serum IgE.3. There was no apparent correlation between the weights of newborn babies and their cord serum IgE levels.4. There was no difference between the two sexes in the cord serum IgE levels.5. Although there was no correlation between the gestational period and the cord serum IgE level from 37 to 42 weeks of pregnancy, statistically significant difference in the IgE level was observed between the group of 37-38weeks of gestation and that of over 41weeks.6. A statistically significant correlation (r=0.1518, n=210) was found between the maternal and cord serum IgE levels, and the group of high maternal IgE levels showed significantly high IgE levels in the cord serum IgE.These results suggest that the maternal IgE concentration is the most important factor of the cord serum IgE.
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