THE CORRELATION BETWEEN AGES AND ANTIGEN-SPECIFIC IgG4 ANTIBODIES IN CHILDREN WHO HAVE HAD NO ALLERGIC DISEASES

概要

論文の詳細を見る
We studied the correlation between ages and the specific IgG4 antibodies to Dermatophagoides pteronyssinus (Dp), egg-white, cow's milk, soybean in 66 children who had no allergic diseases. Thirty-nine boys and twenty-seven girls were studied. Their ages ranged from one month to 12 years old.A few children had the specific IgG4 antibody to Dp. Egg-white-specific IgG4 antibody was detected in chidren after 5 months of age, and 75%-92% in those after 2 years old. Cow's milk-specific IgG4 antibody was already present in early infancy, and was especially detected with high frequency in 3 to 4 years-old children. Soybean-specific IgG4 antibody was produced in a few cases after 1 year old.These results suggest that the antigen-specific IgG4 antibodies are produced with high frequency in children who have had no allergic diseases.
日本小児アレルギー学会の論文