TOTAL IgE AND SPECIFIC IgG ANTIBODIES AGAINST FOOD ANTIGENS IN PREMATURE INFANTS

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Total IgE and antigen (hen's egg and cow's milk) specific IgG antibodies in the serum of 42 premature infants were measured. IgE values were low at birth, but sigunificantly increased at more than one month of age. At 33 weeks for the corrected gestational age or older, some of the IgE values became more than 1IU/ml. Infants whose specific cow's milk IgG titer were high tended to show high IgE values.Specific cow's milk IgG titers significantly increased at more than one month of age. Both at more than one month and more than 36 weeks for the corrected gestational and over 90 times cow's milk feedings, some of specific cow's milk IgG titers exceeded 20U. Infants with an allergic family history tended to display high specific cow's milk IgG titers. It is suggested that the capacity to produce specific cow's milk IgG antibody is possibly related with hereditary factors.Hen's egg IgG titers decreased over time.
日本小児アレルギー学会の論文