DETECTION OF SPECIFIC IgE ANTIBODIES TO GELATIN IN HALTHY AND ALLERGIC CHILDREN

概要

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Gelatin in live vaccines has been considered to be a major substance to induce allergic reactions. In the present study, we measured anti-gelatin IgE antibodies in healthy and allergic children to clarify the sensitization with gelatin in childhood. Anti-gelatin IgE antibody was detected in one of 551 healthy children (0.18%) and 5 of 219 allergic children (2.3%).Among 5 allergic children, three had severe atopic dermatitis and two had moderate bronchial asthma. No allergic reaction was observed in all five children, when they was immunizated with gelatin-contained vaccines and foods containing gelatin.
日本小児アレルギー学会の論文