USEFULNESS OF PEF MONITORING ON ACUTE ASTHMA ATTACK AND RECOVERY PERIOD
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To evaluate the usefulness of PEF measurement on acute asthma attack in children following studies were performed.1. Initially we evaluated PEF before and after β-agonist inhalation on acute asthma attacks (n=426) in 145 asthmatic children (males 86 cases, females 59 cases, age 6 to 17years-old) at outpatient clinic in our hospital, and those episodes were divided into three groups, which were admission group (n=122), admission within 24 hrs group (n=27), and non-admission group (n=277). Mean% PEF before (after) inhaled β-agonist were significantly different between three groups, with the mean of 31.6% (47.3%), 41.0% (71.6%), and 50.5% (81.6%) respectively.2. Next, we investigated changes in % PEF and other parameters (FEV1.0, V50 and SpO2) day by day in 87 admissions due to asthma attacks with no respiratory complications such as pneumonia and atelectasis in 81 asthmatic children (male 45 cases, females 36 cases, age 6-16 years-old). Percent PEF was tended to improve more faster than % V50. Percent PEF before and after inhalation of β-agonist on the second day was 55.6% and 74.2% respectively, which were significantly higher than the first day of admission, while SpO2 on the first and second day were 94.1% and 94.1% respectively, showing no significant improvement.These results suggest that measuring PEF before and after inhaled β-agonist on acute asthma attack is useful to determine treatment plan, including prediction of exacerbation after sent home. However, not only PEF but also assessment of SpO2 and peripheral airways obstruction should be measured for evaluating the recovery from severe attacks.
- 日本小児アレルギー学会の論文
日本小児アレルギー学会 | 論文
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