CLINICAL AND FOLLOW-UP STUDIES OF NINE CHILDREN WITH FOOD-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS DIAGNOSED BY CLINICAL COURSES

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Clinical features and a questionnaire follow-up study of nine children with food-dependent exercise-induced anaphylaxis (FEA) were reported. They were 7 boys and 2 girls, whose ages at onset ranged from 9 to 16 years. The causative foods were shelfish in 5 cases, wheat in 3 cases, but not identified in one case. The intervals between meal ingestion and exercise ranged from 0.5 to 4 hours. From questionnaire data obtained the prognoses were different in shelfish allergy group and the other allergy groups. In shelfish allergy group, all patients have been eliminated responsible foods and cosequently no limitation of exercise was needed at school. Only one episode of FEA has been recurred by accidental ingestion of shrimp. 3 out of 5 continued strenuous exercise. On the other hand, in wheat and other allergy groups, complete elimination of antigens at school was almost impossible, so that all patients had experienced recurrence of anaphylaxis at school, in spite of limitation of exercise during and after school hours. The present study showed that it was necessary for management of school children with FEA, to give appropriate informations to teachers coaches, and nurses at school.
日本小児アレルギー学会の論文