THE SIGNIFICANCE OF ORAL CHALLENGE TEST WITH A BOOLED EGG WHITE

概要

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Forty-four patients with positive IgE antibody (RAST score>2) to egg white and a history of egg white ingestion received oral challenge test with freeze-dried egg white, and 20 of the 44 cases was challenged with boiled egg white, too.Disagreement between parents' judgment of patients' egg allergy and oral challenge test results with freeze-dried egg white was observed in 21 (47.7%) of 44 subjects.The reason might be that their parents made a judgment of patients' egg allergy based on the history of ingestion of heated or processed egg white.Eleven of 14 patients with positive results of challenge tests with freeze-dried egg white showed negative challenge results with boiled egg white.We could not expect the results of oral challenge test with boiled egg white by IgE antibody titers to freeze-dried egg white.Then, it is necessary to perform oral challenge test with not only freeze-dried egg white but also boiled egg white for more detailed dietary instruction to egg arellgic patients.
日本小児アレルギー学会の論文