Mediastinal Non-Hodgkin's Lymphoma in Young Children with Severe Dyspnea.
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概要
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Two young children exhibiting severe dyspnea caused by mediastinal non-Hodgkin's lymphoma (NHL) are reported. Both patients were initially treated for bronchial asthma. A 3-year-old boy (patient 1) was referred to our hospital because of progressive dyspnea and an increase in the size of a mediastinal mass. On admission, superior vena cava syndrome and severe cyanosis were found. NHL was diagnosed by biopsy of a cervical lymph node within 23 hours of admission. Tracheostomy was performed, and induction chemotherapy under the mechanical ventilation for 23 days was successful to achieve a complete remission. A 5-year-old boy (patient 2) was referred to our hospital because of progressive dyspnea and mediastinal shift accompanied by right pleural effusion. NHL was diagnosed by cytology of the tumor cells obtained from the effusion. The symptoms improved dramatically following induction chemotherapy, but he died 6 days after initiation of induction chemotherapy because of the abrupt respiratory distress. Mediastinal NHL among younger childhood is rare, which resulted in delayed diagnosis. Such patients require prompt and accurate diagnosis and should be treated as an "oncologic emergency" case.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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