Alterations of Soluble Thrombomodulin in Neonates, Infants and Children.
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概要
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Thrombomodulin (TM) is a vascular endothelial cell membrane glycoprotein which complexes with thrombin to accelerate protein C activation. Recently, its soluble forms have also been demonstrated to be present in plasma and urine. These soluble forms of TM are expected to be a specific parameter of endothelial cell injury. In this study, plasma and urine levels of TM were investigated in neonates, infants and children. There was a good correlation between plasma TM and urinary TM levels in healthy children. The level of soluble TM in neonates and infants is higher than that in adults, and it decreases to adult levels in children.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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