Autologous Bone Marrow Transplantation in Children with Leukemia Lymphoma Syndrome.
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概要
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Five children with leukemia lymphoma syndrome (LLS) in complete remission (CR) were received high-dose chemotherapy and/or total body irradiation followed by autologous bone marrow transplantation (ABMT). Autologous bone marrow was harvested at 1st CR in all patients and purged with 4-hydroperoxycyclophosphamide (4HC). Although one patient autografted in 2nd CR died of relapse, the other three patients in 1st CR are alive without relapse at +22m, +20m, + 11m. Especially, the treatment in two of them was finished within nine months from their diagnosis. Adverse effects of ABMT were a few and tolerable by the supportive cares. ABMT purged with 4HC would be effective and useful treatment in children with LLS.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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