Effect on the Oral Condition and Oral Bacteria Flora by a Remission Induction Therapy Session in Children with Acute Lymphoblastic Leukemia.
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概要
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It is known that stomatitis is often observed in children with acute lymphoblastic leukemia (ALL) and it is often the source of ingestion difficulties. An oral rinse may be used to prevent or treat the lesions caused by gingivitis or stomatitis. The purpose of this research was to determine the most effective rinse for use in the treatment of gingivitis and stomatitis among children with ALL at Kobe children's hospital. As a basis for determing the best rinse for use in the treatment of children with ALL, 2 oral symptoms were clinically observed : lesions, their location and their length of duration, and the fluctuation in the amount of bacteria flora. The findings were as follows : 1) Stomatitis was observed in almost all cases. 2) Bleeding from the gingival region corresponded to a decrease in blood platelets in cases which involved the use of anti-leukemic drugs. 3) In almost all cases where etoposide was used, the clinical findings were observed in the gingival region. 4) The total amount of oral bacteria decreased after administration of the antibiotics. 5) In the case of children who have ALL, oral Candidiasis developed more often than in healthy children.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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