Hepatosplenic Candidiasis in a Patient with Acute Leukemia.
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概要
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A 15-year old girl with newly diagnosed ALL became febrile with neutropenia after induction chemotherapy. She was started on fluconazole empirically with antibiotics. Although, her fever disappeared when neutropenia was recovered, her serum CRP levels remained elevated. Abdominal CT showed multiple small lucencies throughout the liver, the spleen, and the left kidney. Multiple blood cultures and urine cultures were negative, but urinary fungus was detected by micros-copy, and Candida was isolated in her stools. The fluconazole dosage was increased, then, her CRP level returned to normal. Thereafter, her CRP levels were increased after each course of consolidation chemotherapy, and decreased when neutropenia was recovered. Ultrasound detected "the target lesion" earlier than CT in this patient. One year later, the lesions revealed the findings representing calcifications. She has been in complete remission as of now, receiving maintenance chemotherapy with fluconazole.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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