An Infantile Case of Microgranular Variant of Acute Promyelocytic Leukemia.
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概要
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An infantile case of microgranular variant of acute promyelocytic leukemia (APL) is reported. The patient was a 1-year-old girl who suffered from disseminated intravascular coagulation and chromosomal abnormality of 15 ; 17 translocation. WBC count at diagnosis was 180, 000/μl. Blasts appeared not only in bone marrow but also in urine and CSF. Distinctive features of the blasts were bilobed nuclei, "dust-like" azurophilic inclusions and no faggots in the cytoplasmas. Shs was in remission after three courses of chemotherapy regimens. After ten months from diagnosis she died of fulminant hepatitis of type B. Previously reported cases with APL in childhood including our case were also reviewed.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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