Bilineal leukemia occuring 15 years after diagnosis of acute lymphoblastic leukemia.
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概要
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A 11-year-old girl was diagnosed as having an acute lymphoblastic leukemia (ALL) in April 1973, and she successfully completed chemotherapy of 5-year duration. In January 1988, she was found to have a leukemia involving bone marrow and central nervous system simultaneously. At this time, blast cells were peroxidase (Pox) negative and possessed early B cell markers. During early induction therapy, however, Pox-positive blast cells became predominant and they exhibited myeloid antigens on their surface. She was considered to have a bilineal leukemia. After having obtained a complete remission with combination chemotherapy, she experienced several relapses and died 18 months after developing the bilineal leukemia, and 195 months after the initial diagnosis of ALL.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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