Effect of Repeated Oral Vitamin K Administration to Prevent Vitamin K Deficiency in Infants
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概要
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The measurement of Normotest (Hepaplastintest, Eisai Co., Japan) values for infants was carried out at 5 days, 14 days, and 1 month of age in 151 healthy infants, each having received 2 mg of vitamin K<SUP>2</SUP> orally at first feeding (group A), or at first feeding and 5 days of age (group B). These measurements revealed a rising in the mean Normotest values. There was no significant difference in the Normotest value between breast-fed and mixed-fed infants at 5 days and 1 month of age in these two groups. The breast-fed infants showed a significantly lower Normostest value at 14 days of age in group A than that in group B. The number of infants with a low Normotest value (<40%) was 11 and 4 out of 151 cases at 5 days and 14 days, respectively, but none of the breast-fed infants in group B showed a low Normotest value at 14 days of age. The results show the possibility that repeated oral vitamin K<SUP>2</SUP> administration increases the Normotest value, especially in breast-fed infants, and prevents vitamin K deficiency in infants.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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