A Case of Down Syndrome with Transient Abnormal Myelopoiesis and Nonsyndromic Paucity of Interlobular Bile Ducts
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We performed a liver biopsy for a case of Down syndrome with transient abnormal myelopoiesis (TAM) and prolonged liver dysfunction. Pathologic findings showed neither hepatic fibrosis nor infiltration by megakaryoblasts, being compatible with TAM, but showed a paucity of interlobular bile ducts and intracellular cholestasis, resulting in the diagnosis of nonsyndromic paucity of interlobular bile ducts (NS-PILBD). If patients with TAM show prolonged hepatic dysfunction, we consider NS-PILBD as one of the differential diagnoses.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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