Successful Treatment with Unrelated Donor Bone Marrow Transplantation in a Young Girl with t(6;9)(p23;q34) Positive Acute Myeloid Leukemia
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概要
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A 6-year-old girl, who was diagnosed as acute myeloid leukemia (AML-M2) with t (6;9) (p23;q24) and with expression of the DAK-CAN fusion protein, treated on the CCLSG AML9805 protocol. A complete remission (CR) was achieved after induction and salvage chemotherapy. She underwent allogenic bone marrow transplantation (BMT) from an unrelated donor. The pre-conditioning regimen included busulfan and melphalan. The clinical course was uneventful, and hematological recovery occurred rapidly. She was in CR with negative PCR for DEK-CAN and survived for five years. It may be suggested that achieving DEK-CAN negativity after BMT in the first CR leads to a good prognosis for t (6;9) -AML.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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