Salvage Therapy with R-CHOP in a Patient with Burkitt's Lymphoma Involved Perforation of the Appendix and Advanced Fatty Liver
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We report here a case of Burkitt's lymphoma treated with R-CHOP regimen as salvage chemotherapy. A 13-year old boy was admitted due to abdominal distention and testicular swelling. He was diagnosed as having Burkitt's lymphoma stage III by pathological examination and clinical imaging. Because a perforation of the appendix and acute pancreatitis occurred, induction chemotherapy was discontinued. Rituximab was administered to prevent progression of lymphoma during treatment of the complications, and he achieved his first complete remission. Intensive chemotherapy was not able to be performed because of severe fatty liver and recurrent infection related to hypogammaglobulinemia. Eight cycles of R-CHOP regimen consisting of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone were performed as salvage therapy. The patient remains in complete remission after 14 months. R-CHOP regimen might be well tolerated for salvage therapy of Burkitt lymphoma with complications.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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