A Boy with Acute Lymphoblastic Leukemia (ALL) Presenting Relapse of Renal Masses after Bone Marrow Transplantation
スポンサーリンク
概要
- 論文の詳細を見る
Renal involvement of acute lymphoblastic leukemia (ALL) had been frequently reported in autopsy cases in the past. Current progress of the treatment decreased this problem. We report a 4-year-old boy presenting isolated renal masses at the time of second recurrence of ALL after receiving bone marrow transplantation (BMT). After 7 months of complete remission with conventional chemotherapy, he developed the first bone marrow relapse. An allogeneic BMT was performed from a HLA-identical donor of his brother in partial remission. However, 124 days after BMT, abdominal ultrasonography unexpectedly showed bilateral renal masses. Thorough medical examination showed isolated renal invasion of the leukemic cells. This suggested that the extramedullary masses were formed by surviving leukemic cells in peripheral organs due to an insufficient effect of graft-versus-leukemia (GVL) rather than that in the marrow. During the follow-up periods after BMT, regular ultrasonography of abdomen must be done to detect isolated extramedullary involvement. Urinary cytology should be useful if indicated.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
- The Parent's Emotional Adaptation to the Children's Malignant Disease
- Side Effect of Cranial Radiation in Childhood Acute Leukemia
- Red Blood Cell Volume Distribution Width in Normal Children and in the Patients with Various Kinds of Hematological Disorders.
- Effective Conditioning of Donors for Granulocyte Transfusions with Recombinant Human Granulocyte Colony-Stimulating Factor.
- Two Infant Girls of CNS Leukemia with Chronic Subdural Hematoma