A Case of Vitamin B12-Deficient Megaloblastic Anemia with Generalized Pigmentation.
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概要
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We encountered a 12-year-old boy with vitamin B<SUB>12</SUB>-deficient megaloblastic anemia complicated with generalized pigmentation. The patient was administered vitamin B<SUB>12</SUB> subcutaneously, and his anemia improved in approximately eight months. His skin pigmentation also improved gradually, and it almost completely disappeared in the course of three years. This patient experienced no other complications such as autoimmune or endocrine disorders ; therefore his pigmentation is considered to be due to vitamin B<SUB>12</SUB> deficiency. Pigmentation is an extremely rare complication of vitamin B<SUB>12</SUB>-deficient megaloblastic anemia, and is not described even in textbooks. However, a diagnosis of vitamin B<SUB>12</SUB>-deficient megaloblastic anemia should be considered in patients showing pigmentation, especially those who complain of easy fatigability, and a blood examination should be performed at an early stage of the disease.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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