Late Effects in Children Treated for Acute Lymphoblastic Leukemia: Height and Weight Pattern after Cessation of Chemotherapy.:Height and Weight Pattern after Cessation of Chemotherapy
スポンサーリンク
概要
- 論文の詳細を見る
The growth of childhood acute lymphoblastic leukemia (ALL) was studied in 215 patients (140 boys and 75 girls) who had remained in remission for more than a year after the completion of their maintenance therapy. The median age at diagnosis was 4.2 years, and the median duration of follow-up from the time of diagnosis was 6.0 years. The children had been treated by ALL-protocol of the Children's Cancer and Leukemia Study Group. Heights and weights were examined at diagnoses up to 10 years after the cessation of chemotherapy. The Z score, which reflects the deviation of height and weight measurements from the population mean, was used to assess height and weight changes. The mean height Z score was-0.36 SD at the cessation of chemotherapy and-0.59 SD at 5 years. Seven years after the cessation of chemotherapy, the girls showed a decrease in the mean height Z score (-1.32 SD) compared with the boys (0.16 SD) (<I>p</I><0.01). The mean weight Z score was 0.36 SD at the cessation of chemotherapy and-0.36 SD at 5 years. Obesity was seen in 7.9% at the cessation of chemotherapy. No obvious correlation between the administered cranial irradiation and growth failure was found. The short stature seen in patients treated for ALL is more pronounced in girls than in boys.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
- The Parent's Emotional Adaptation to the Children's Malignant Disease
- Side Effect of Cranial Radiation in Childhood Acute Leukemia
- Red Blood Cell Volume Distribution Width in Normal Children and in the Patients with Various Kinds of Hematological Disorders.
- Effective Conditioning of Donors for Granulocyte Transfusions with Recombinant Human Granulocyte Colony-Stimulating Factor.
- Two Infant Girls of CNS Leukemia with Chronic Subdural Hematoma