A Refractory AML-M7 in a Down's Syndrome Boy Who Developed Bronchiolitis Obliterance after Successful Unrelated Cord Blood Transplantation.
スポンサーリンク
概要
- 論文の詳細を見る
We report a one-year-old boy with Down's syndrome and AML-M7, which was primarily refractory to chemotherapy. He was successfully induced into remission with a cord blood transplantation from an HLA A-locus mismatched unrelated donor following a conditioning regimen that consisted of cyclophosphamide, busulfan, and L-PAM. A grade III acute GVHD developed on day 7 and was well controlled with bolus methyl-prednisolone (mPSL). Severe bronchiolitis obliterance (BO) developed on day 91 and was treated with a megadose mPSL therapy (100 mg/kg/day × 7 days). The patient has been on a respirator because of extreme hypercapnia, but the BO has stopped progressing and is now stable. He is in hematological remission at 10 months posttransplant.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
- The Parent's Emotional Adaptation to the Children's Malignant Disease
- Side Effect of Cranial Radiation in Childhood Acute Leukemia
- Red Blood Cell Volume Distribution Width in Normal Children and in the Patients with Various Kinds of Hematological Disorders.
- Effective Conditioning of Donors for Granulocyte Transfusions with Recombinant Human Granulocyte Colony-Stimulating Factor.
- Two Infant Girls of CNS Leukemia with Chronic Subdural Hematoma