Population-Based Epidemiological Study of Childhood and Infantile Leukemia in Kyoto, 1990-1994.
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概要
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The incidence and residence distribution of pediatric hematopoietic malignancies in children under 15 years of age were surveyed. Eighty-three children with hematopoietic malignancies were diagnosed during the period from 1990 through 1994; 57 patients were acute lymphocytic leukemia (ALL) (68.7%), 19 (22.9%) acute nonlymphocytic leukemia (ANLL), 2 (2.4%) myelodysplastic syndrome (MDS), 4 (4.8%) chronic myeloid leuke-mia (CML), and 1 (1.2%) juvenile myelomonocytic leukemia (JMML). The population-based incidence was 3.70 per 100, 000 persons a year as a whole; the incidence of ALL, ANLL, MDS, CML, and JMML was 2.54, 0.85, 0.09, 0.18, and 0.04, respectively. These results were comparable with the results reported from other countries. The incidence in four districts in Kyoto Prefecture was as follows : 1.59 in Tango-Chutan district, 2.04 in Chubu, 4.95 in Kyoto-Otokuni, and 2.24 in Minamiyamashiro-Souraku. The incidence was significantly high in the Kyoto-Otokuni district (<I>p</I> = 0.023) and low in the Tango-Chutan district (<I>p</I> = 0.026). Eight infant leukemia patients (ALL 5, ANLL 3) developed out of 83 leukemia (9.6%) during the same period. The incidence was 6.62, which seemed to be higher than the previously reported incidence of 3 or 4 per 100, 000 persons a year. It should be elucidated why the incidence of pediatric leukemia was high in the Kyoto-Otokuni district.
- 特定非営利活動法人 日本小児血液・がん学会の論文
特定非営利活動法人 日本小児血液・がん学会 | 論文
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