肝,胆道,膵疾患における真菌感染症--剖検例での検討
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概要
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A clinical assessment of fungal infection in hepatobiliary and pancreatic diseases during 1975 and 1991 was made and 25 cases of systemic mycosis were noted. Among 25 cases there were 20 liver diseases (hepatocellular carcinoma 12, liver cirrhosis 5, fulminant hepatitis 2, polyarteriris nodosa 1), 2 cases of gallbladder cancer and 3 cases of pancreatic cancer. The fungus was consisted of 14 cases (56%) of <I>Candida</I>, 9 cases of <I>Aspergillus</I> (36%), and 2 cases of <I>Cryptococcus</I> (8%).Fungal infection was most frequent in the lung (8 cases) and esophagus (6 cases), but rarely in the stomach, lyrnphnode, liver, thyroid, kidney and gallbladder. Generalized fungus infection was noted in four cases (16%).<BR>Fatal fungal infection was complicated in liver cirrhosis (2 cases), fulminant hepatitis (one case), gallbladder cancer (one case) and cystadenocarcinoma of the pancreas (one case). In five fatal cases three cases of <I>Aspergillus</I> pneumonia and two cases of <I>Candida</I> septicemia were included. Glucocorticoid was used in 13 cases (52%) and anti-cancer drugs was administered in two cases (12%). However, in 9 cases (36%) without treatment of glucocorticoid or anti-cancer drug fungal infection was detected. In conclusion, there is a possibility of fungal infection in grave hepatic diseases and empirical administration of anti-fungal agent may be necessary.
- 日本感染症学会の論文
日本感染症学会 | 論文
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